Fully loaded micromotors for combinatorial delivery and autonomous release of cargoes

Small. 2014 Jul 23;10(14):2830-3, 2743. doi: 10.1002/smll.201303646. Epub 2014 Apr 6.

Abstract

Integrating functional self-propelled Zinc micromotors are created by coup-ling electrodeposition with hard dual-templating synthesis. The micromotors concurrently possess four robust functions including a remarkably high loading capacity, combinatorial delivery of cargoes, autonomous release of encapsulated payloads, and self-destruction. This concept could be expanded to simultaneous encapsulation of various payloads for different functionalities such as therapy, diagnostics, and imaging.

Keywords: cargo transport; drug delivery; micromachines; zinc.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bioengineering
  • Drug Delivery Systems / methods*
  • Gold / chemistry
  • Metal Nanoparticles / chemistry*
  • Metal Nanoparticles / ultrastructure
  • Microscopy, Electron, Scanning
  • Motion
  • Nanocapsules / chemistry
  • Nanocapsules / ultrastructure
  • Nanotechnology
  • Silicon Dioxide / chemistry
  • Spectrometry, X-Ray Emission
  • Zinc / chemistry

Substances

  • Nanocapsules
  • Gold
  • Silicon Dioxide
  • Zinc