Normal CYP3A activity during arsenic trioxide therapy

Ann Hematol. 2014 Nov;93(11):1941-2. doi: 10.1007/s00277-014-2076-2. Epub 2014 Apr 16.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Arsenic Trioxide
  • Arsenicals / administration & dosage
  • Arsenicals / metabolism*
  • Cytochrome P-450 CYP3A / blood*
  • Enzyme Activation / drug effects
  • Enzyme Activation / physiology
  • Humans
  • Leukemia, Promyelocytic, Acute / blood*
  • Leukemia, Promyelocytic, Acute / drug therapy*
  • Male
  • Middle Aged
  • Oxides / administration & dosage
  • Oxides / metabolism*

Substances

  • Arsenicals
  • Oxides
  • CYP3A protein, human
  • Cytochrome P-450 CYP3A
  • Arsenic Trioxide