Full-genome analysis was conducted on the first isolate of a highly pathogenic avian influenza A(H5N1) virus from a human in North America. The virus has a hemagglutinin gene of clade 2.3.2.1c and is a reassortant with an H9N2 subtype lineage polymerase basic 2 gene. No mutations conferring resistance to adamantanes or neuraminidase inhibitors were found.
Keywords: Canada; H5N1 subtype; H9N2 subtype; HPAI; North America; avian influenza; full genome; genome analysis; highly pathogenic avian influenza; human; influenza; influenza A; reassortant; viruses.