Calcium involved in the poly(γ-glutamic acid)-mediated promotion of Chinese cabbage nitrogen metabolism

Plant Physiol Biochem. 2014 Jul:80:144-52. doi: 10.1016/j.plaphy.2014.03.036. Epub 2014 Apr 12.

Abstract

Plant growth can reportedly be promoted by poly(γ-glutamic acid) (γ-PGA). However, the underlying mechanism is unknown. To reveal the mechanism of γ-PGA, we designed an experiment that investigated the effect of γ-PGA on the nitrogen metabolism of Chinese cabbage hydroponic cultured at different calcium (Ca) levels and varied exogenous Ca(2+) inhibitors. The results showed that nitrate reductase (NR), glutamine synthetase (GS), glutamate synthase, and glutamate dehydrogenase activities in leaves and roots were obviously enhanced by γ-PGA at the normal Ca(2+) level (4.0 mM). Meanwhile, γ-PGA increased the content of total nitrogen, soluble protein, and soluble amino acids in leaves. However, the promotional effect of γ-PGA on fresh weight weakened when Ca(2+) was inadequate. Moreover, γ-PGA not only induced the influx of extracellular Ca(2+) and Ca(2+) in organelles into cytoplasm, but also increased the Ca(2+)-ATPase level to modify Ca(2+) homeostasis in plant cells. In addition, exogenous Ca(2+) inhibitors significantly suppressed the γ-PGA-mediated promotion of cytoplasmic free Ca(2+) level, calmodulin (CaM) content, GS and glutamate dehydrogenase activities. In summary, γ-PGA accelerated the nitrogen metabolism of plants through the Ca(2+)/CaM signaling pathway, thereby improving the growth of the plant.

Keywords: Calcium; Chinese cabbage; Nitrogen metabolism; Poly(γ-glutamic acid); Subcellular compartments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brassica / drug effects*
  • Brassica / metabolism*
  • Calcium / metabolism
  • Calcium / pharmacology*
  • Glutamate Synthase / metabolism
  • Glutamate-Ammonia Ligase / metabolism
  • Nitrate Reductase / metabolism
  • Nitrogen / metabolism*
  • Polyglutamic Acid / analogs & derivatives*
  • Polyglutamic Acid / pharmacology

Substances

  • poly(gamma-glutamic acid)
  • Polyglutamic Acid
  • Glutamate Synthase
  • Nitrate Reductase
  • Glutamate-Ammonia Ligase
  • Nitrogen
  • Calcium