First case of nontuberculous mycobacterial lung disease caused by Mycobacterium marseillense in a patient with systemic lupus erythematosus

Su-Young Kim; Hongseok Yoo; Byeong-Ho Jeong; Kyeongman Jeon; Young Eun Ha; Hee Jae Huh; Chang-Seok Ki; Nam Yong Lee; Sung Jae Shin; Won-Jung Koh

doi:10.1016/j.diagmicrobio.2014.03.019

First case of nontuberculous mycobacterial lung disease caused by Mycobacterium marseillense in a patient with systemic lupus erythematosus

Diagn Microbiol Infect Dis. 2014 Jul;79(3):355-7. doi: 10.1016/j.diagmicrobio.2014.03.019. Epub 2014 Mar 29.

Authors

Affiliations

¹ Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
² Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
³ Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
⁴ Department of Microbiology, Yonsei University College of Medicine, Seoul, Republic of Korea.
⁵ Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address: [email protected].

PMID: 24768296
DOI: 10.1016/j.diagmicrobio.2014.03.019

Abstract

Mycobacterium marseillense was designated as a new species within Mycobacterium avium complex. We report the first case of M. marseillense lung disease in a patient with systemic lupus erythematosus. All serial isolates were identified as M. marseillense by multilocus sequence analysis, based on hsp65, 16S-23S rRNA internal transcribed spacer, and 16S rRNA fragments.

Keywords: Mycobacterium avium complex; Mycobacterium marseillense; Nontuberculous mycobacteria.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Proteins / genetics
Chaperonin 60 / genetics
Cluster Analysis
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
DNA, Ribosomal / chemistry
DNA, Ribosomal / genetics
DNA, Ribosomal Spacer / chemistry
DNA, Ribosomal Spacer / genetics
Humans
Lupus Erythematosus, Systemic / complications*
Male
Middle Aged
Multilocus Sequence Typing
Mycobacterium Infections, Nontuberculous / diagnosis*
Mycobacterium Infections, Nontuberculous / microbiology
Mycobacterium avium Complex / classification
Mycobacterium avium Complex / genetics
Mycobacterium avium Complex / isolation & purification*
Phylogeny
Pneumonia, Bacterial / diagnosis*
Pneumonia, Bacterial / microbiology
RNA, Ribosomal, 16S / genetics

Substances

Bacterial Proteins
Chaperonin 60
DNA, Bacterial
DNA, Ribosomal
DNA, Ribosomal Spacer
RNA, Ribosomal, 16S
heat-shock protein 65, Mycobacterium