Symptom prevalence and physiologic biomarkers among adolescents using a mobile phone intervention following hematopoietic stem cell transplantation

Oncol Nurs Forum. 2014 May;41(3):229-36. doi: 10.1188/14.ONF.229-236.

Abstract

Purpose/objectives: To examine symptom reports and physiologic parameters in adolescents using the Eating After Transplant (EAT!) intervention during recovery after hematopoietic stem cell transplantation (HSCT).

Design: Repeated measures design.

Setting: HSCT service at a pediatric teaching institution in the southern United States.

Sample: 16 adolescents recovering from a first-time allogeneic HSCT.

Methods: Use of EAT! was monitored electronically, symptom reports were obtained from a questionnaire, and physiologic parameters were obtained from the medical record at HSCT hospital discharge and 20, 40, and 60 days postdischarge.

Main research variables: EAT! use, symptom prevalence, symptom-related distress, and physiologic parameters including weight, body mass index (BMI), pre-albumin, and albumin.

Findings: Symptom prevalence was highest at hospital discharge and steadily declined; however, mean symptom distress scores remained stable. Mean weight and BMI significantly declined during the first 60 days postdischarge; pre-albumin and albumin markers were unchanged. No correlation was noted among use of EAT! and any research variables.

Conclusions: The most frequent symptoms were not always the most distressing symptoms. Weight and BMI significantly declined during HSCT recovery.

Implications for nursing: Nurses should assess symptom frequency and distress to fully understand patients' symptom experiences. Nurses should monitor weight and BMI throughout HSCT recovery.

Keywords: pediatric oncology; quantitative nursing research; stem cell/marrow trans-plantation.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Albumins / analysis*
  • Biomarkers / blood*
  • Body Mass Index
  • Body Weight
  • Cell Phone*
  • Child
  • Electronic Health Records
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Hematopoietic Stem Cell Transplantation / nursing*
  • Humans
  • Information Dissemination / methods*
  • Male
  • Neoplasms / blood*
  • Neoplasms / therapy*
  • Nurse's Role
  • Pediatric Nursing
  • Texas

Substances

  • Albumins
  • Biomarkers