Hemodynamic-directed cardiopulmonary resuscitation during in-hospital cardiac arrest

Resuscitation. 2014 Aug;85(8):983-6. doi: 10.1016/j.resuscitation.2014.04.015. Epub 2014 Apr 28.

Abstract

Cardiopulmonary resuscitation (CPR) guidelines assume that cardiac arrest victims can be treated with a uniform chest compression (CC) depth and a standardized interval administration of vasopressor drugs. This non-personalized approach does not incorporate a patient's individualized response into ongoing resuscitative efforts. In previously reported porcine models of hypoxic and normoxic ventricular fibrillation (VF), a hemodynamic-directed resuscitation improved short-term survival compared to current practice guidelines. Skilled in-hospital rescuers should be trained to tailor resuscitation efforts to the individual patient's physiology. Such a strategy would be a major paradigm shift in the treatment of in-hospital cardiac arrest victims.

Keywords: Arterial blood pressure; Cardiac arrest; Cardiopulmonary resuscitation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cardiopulmonary Resuscitation / methods*
  • Heart Arrest / physiopathology
  • Heart Arrest / therapy*
  • Hemodynamics*
  • Humans