[Systemic cytomegalovirus infection: changes in serum calcium and magnesium levels with foscarnet treatment]

An Pediatr (Barc). 2015 Jan;82(1):e170-4. doi: 10.1016/j.anpedi.2014.03.021. Epub 2014 Apr 29.
[Article in Spanish]

Abstract

Cytomegalovirus infection is common in cardiac transplant patients. Foscarnet is used, with limited evidence, as second-line treatment after ganciclovir failure in these patients. We describe the case of a paediatric cardiac transplant patient who developed electrolyte disturbances during foscarnet treatment for cytomegalovirus infection. The infection resolved after 6 weeks of treatment. Low ionized calcium and magnesium levels were observed during the drug infusion, which were treated with supplements. The serum levels reverted to normal after drug withdrawal.

Keywords: Foscarnet, Citomegalovirus, Hipocalcemia, Hipomagnesemia, Reacción adversa; Foscarnet, Cytomegalovirus, Hypocalcemia, Hypomagnesemia, Adverse drug reaction.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / therapeutic use*
  • Calcium / blood*
  • Child, Preschool
  • Cytomegalovirus Infections / blood*
  • Cytomegalovirus Infections / drug therapy*
  • Foscarnet / therapeutic use*
  • Humans
  • Magnesium / blood*
  • Male

Substances

  • Antiviral Agents
  • Foscarnet
  • Magnesium
  • Calcium