Risk factors of nocturia (two or more voids per night) in Chinese people older than 40 years

Neurourol Urodyn. 2015 Aug;34(6):566-70. doi: 10.1002/nau.22623. Epub 2014 Apr 30.

Abstract

Aims: To explore the risk factors of nocturia in Chinese inhabitants aged ≥40 years.

Methods: A randomized, community-based, cross-sectional study was performed on 10,160 inhabitants ≥40 years old in mainland China, via a stratified sampling approach. A questionnaire, including socio-demographics, lifestyle factors and medical history, was completed. Nocturia was defined as a threshold of two or more voids per night. Differences in prevalence between age and gender groups were ascertained by the chi-squared test. Gender-related factors were evaluated by multivariate logistic regression analysis. P < 0.05 was considered to be statistically significant.

Results: Data on 9,637 (94.9%) people aged 59.6 ± 9.7 years qualified for final statistical analysis. The overall prevalence of nocturia was 31.7% (3,053/9,637), and this increased with age (P < 0.001). Nocturia was significantly associated with cardiovascular disease and overactive bladder symptom score (OABSS) (P < 0.05), while sporting activities were protective (P < 0.001). Diabetes mellitus (DM) was significantly correlated with nocturia in men (P < 0.05), whereas hypertension was correlated with nocturia in women (P < 0.05). No correlation was found between nocturia and education level, occupation, civil status, tea consumption, body mass index (BMI), female birth history, and International Prostate Symptom Score.

Conclusions: In Chinese people aged ≥40 years, nocturia is associated with aging, OABSS, cardiovascular disease, hypertension, and DM. Sporting activities are negatively associated with nocturia.

Keywords: aging; cardiovascular disease; diabetes mellitus; elderly people; nocturia; risk factors; sporting activities.

MeSH terms

  • Age Factors
  • Aged
  • Asian People
  • Body Mass Index
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / physiopathology
  • China / epidemiology
  • Cross-Sectional Studies
  • Diabetes Mellitus / urine
  • Female
  • Humans
  • Life Style
  • Male
  • Middle Aged
  • Nocturia / epidemiology*
  • Risk Factors
  • Sex Factors
  • Socioeconomic Factors
  • Surveys and Questionnaires
  • Tea
  • Urinary Bladder, Overactive / epidemiology
  • Urinary Bladder, Overactive / physiopathology

Substances

  • Tea