Mycobacterium arupense flexor tenosynovitis: case report and review of antimicrobial susceptibility profiles for 40 clinical isolates

Elena Beam; Shawn Vasoo; Patricia J Simner; Marco Rizzo; Erin L Mason; Randall C Walker; Sharon M Deml; Barbara A Brown-Elliott; Richard J Wallace Jr; Nancy L Wengenack; Irene G Sia

doi:10.1128/JCM.00277-14

Mycobacterium arupense flexor tenosynovitis: case report and review of antimicrobial susceptibility profiles for 40 clinical isolates

J Clin Microbiol. 2014 Jul;52(7):2706-8. doi: 10.1128/JCM.00277-14. Epub 2014 Apr 30.

Authors

Affiliations

¹ Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
² Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
³ Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
⁴ Department of Microbiology, Mycobacteria/Nocardia Laboratory, The University of Texas Health Science Center, Tyler, Texas, USA.
⁵ Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA [email protected].

Abstract

We describe a case of chronic tenosynovitis in the hand of a 58-year-old cattle farmer. Surgical biopsy specimens grew Mycobacterium arupense. The patient responded to surgery and antimicrobial therapy based on in vitro susceptibility testing. The antimicrobial susceptibility profiles of the isolate from this patient and 39 additional clinical isolates are presented.

Publication types

Case Reports
Review

MeSH terms

Agriculture
Anti-Bacterial Agents / pharmacology
Anti-Bacterial Agents / therapeutic use
Biopsy
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
DNA, Ribosomal / chemistry
DNA, Ribosomal / genetics
Debridement
Humans
Male
Microbial Sensitivity Tests
Middle Aged
Mycobacterium / classification*
Mycobacterium / drug effects
Mycobacterium / isolation & purification*
Mycobacterium Infections, Nontuberculous / diagnosis*
Mycobacterium Infections, Nontuberculous / microbiology
Mycobacterium Infections, Nontuberculous / pathology*
Mycobacterium Infections, Nontuberculous / therapy
RNA, Ribosomal, 16S / genetics
Sequence Analysis, DNA
Tenosynovitis / diagnosis*
Tenosynovitis / microbiology
Tenosynovitis / pathology*
Tenosynovitis / therapy

Substances

Anti-Bacterial Agents
DNA, Bacterial
DNA, Ribosomal
RNA, Ribosomal, 16S