Export and expression: mRNAs deliver new messages for controlling pluripotency

Arven Saunders; Jianlong Wang

doi:10.1016/j.stem.2014.04.009

Export and expression: mRNAs deliver new messages for controlling pluripotency

Cell Stem Cell. 2014 May 1;14(5):549-50. doi: 10.1016/j.stem.2014.04.009.

Authors

Arven Saunders¹, Jianlong Wang²

Affiliations

¹ The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Graduate School of Biological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
² The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Graduate School of Biological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: [email protected].

PMID: 24792108
DOI: 10.1016/j.stem.2014.04.009

Abstract

Fine-tuning of the pluripotency program is executed by a multitude of cellular processes. Two recent studies published in Cell Stem Cell (Wang et al., 2013; Tahmasebi et al., 2014) provide novel insights into the posttranscriptional and translational regulatory mechanisms controlling stem cell pluripotency and somatic cell reprogramming.

Publication types

Comment

MeSH terms

Animals
Cellular Reprogramming / genetics*
Cellular Reprogramming / physiology*
Embryonic Stem Cells / cytology*
Embryonic Stem Cells / metabolism*
Multiprotein Complexes / metabolism*
Pluripotent Stem Cells / metabolism*
RNA Transport / genetics*

Substances

Multiprotein Complexes