Altered binding to the gamma-globin promoter of two erythroid specific nuclear proteins in different HPFH syndromes

Prog Clin Biol Res. 1989:316A:229-36.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Base Sequence
  • Chromosome Deletion
  • Fetal Hemoglobin / genetics
  • Globins / biosynthesis
  • Globins / genetics*
  • Humans
  • Leukemia, Erythroblastic, Acute / pathology
  • Molecular Sequence Data
  • Nuclear Proteins / metabolism*
  • Promoter Regions, Genetic*
  • Repressor Proteins / metabolism
  • Thalassemia / classification
  • Thalassemia / genetics*
  • Transcription Factors / metabolism*
  • Tumor Cells, Cultured

Substances

  • Nuclear Proteins
  • Repressor Proteins
  • Transcription Factors
  • Globins
  • Fetal Hemoglobin