Abstract
A novel metal-free synthesis of quinazolinones via dual amination of sp(3) C-H bonds was developed. The sp(3) carbon in methylarenes or adjacent to a heteroatom in DMSO, DMF or DMA was used as the one carbon synthon.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amination
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Benzenesulfonates / chemistry
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Carbon / chemistry*
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Hydrogen / chemistry*
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Metals / chemistry
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Oxidation-Reduction
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Quantum Theory
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Quinazolinones / chemical synthesis
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Quinazolinones / chemistry*
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Solvents / chemistry
Substances
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Benzenesulfonates
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Metals
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Quinazolinones
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Solvents
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Carbon
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Hydrogen
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4-toluenesulfonic acid