Detoxification of pertussis toxin by site-directed mutagenesis

Adv Exp Med Biol. 1989:251:209-14. doi: 10.1007/978-1-4757-2046-4_20.

Authors

S Cockle¹, S Loosmore, K Radika, G Zealey, H Boux, K Phillips, M Klein

Affiliation

¹ Connaught Research Institute, Willowdale, Ontario, Canada.

PMID: 2481961
DOI: 10.1007/978-1-4757-2046-4_20

No abstract available

MeSH terms

Amino Acid Sequence
Animals
Cells, Cultured
Epitopes
Genes, Bacterial
Histamine Release
Mice
Molecular Sequence Data
Mutation*
NAD
Pertussis Toxin*
Poly(ADP-ribose) Polymerases / metabolism
Transformation, Bacterial
Virulence Factors, Bordetella / genetics
Virulence Factors, Bordetella / immunology
Virulence Factors, Bordetella / metabolism
Virulence Factors, Bordetella / toxicity*

Substances

Epitopes
Virulence Factors, Bordetella
NAD
Poly(ADP-ribose) Polymerases
Pertussis Toxin