Misidentification of Neosartorya pseudofischeri as Aspergillus fumigatus in a lung transplant patient

Reeti Khare; Sounak Gupta; Sana Arif; Mark E Jentoft; Paul J Deziel; Anja C Roden; Mark P Wilhelm; Raymund R Razonable; Nancy L Wengenack

doi:10.1128/JCM.00216-14

Misidentification of Neosartorya pseudofischeri as Aspergillus fumigatus in a lung transplant patient

J Clin Microbiol. 2014 Jul;52(7):2722-5. doi: 10.1128/JCM.00216-14. Epub 2014 May 14.

Authors

Reeti Khare¹, Sounak Gupta², Sana Arif³, Mark E Jentoft², Paul J Deziel⁴, Anja C Roden², Mark P Wilhelm⁵, Raymund R Razonable⁵, Nancy L Wengenack⁶

Affiliations

¹ Division of Clinical Microbiology, Mayo Clinic, Rochester, Minnesota, USA.
² Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota, USA.
³ Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.
⁴ William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, Minnesota, USA.
⁵ Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, Minnesota, USA.
⁶ Division of Clinical Microbiology, Mayo Clinic, Rochester, Minnesota, USA [email protected].

Abstract

We present a case of disseminated Neosartorya pseudofischeri infection in a bilateral lung transplant patient with cystic fibrosis. The organism was originally misidentified from respiratory specimens as Aspergillus fumigatus using colonial and microscopic morphology. DNA sequencing subsequently identified the organism correctly as N. pseudofischeri.

Publication types

Case Reports

MeSH terms

Adult
Aspergillus fumigatus / classification
Aspergillus fumigatus / isolation & purification
Female
Humans
Immunocompromised Host
Lung / microbiology*
Lung Diseases, Fungal / diagnosis*
Lung Diseases, Fungal / microbiology*
Lung Diseases, Fungal / pathology
Microbiological Techniques
Microscopy
Neosartorya / classification*
Neosartorya / isolation & purification*
Sequence Analysis, DNA
Transplant Recipients*