Postinfectious bronchiolitis obliterans in children: the South American contribution

Acta Paediatr. 2014 Sep;103(9):913-21. doi: 10.1111/apa.12689. Epub 2014 Jul 21.

Abstract

Postinfectious bronchiolitis obliterans (PIBO) is an infrequent chronic lung that causes irreversible obstruction and, or, obliteration of the smaller airways. This review particularly focuses on more than 30 studies from South America.

Conclusion: The initial PIBO event occurs in the early years of life and is strongly associated with adenovirus infection and the need for mechanical ventilator support. Treatment requires a multidisciplinary strategy. Multicentre studies are needed to determine progression, optimal management and long-term follow-up.

Keywords: Adenovirus; Bronchiolitis obliterans; Children; Chronic lung disease; South America.

Publication types

  • Review

MeSH terms

  • Bronchiolitis Obliterans / diagnosis
  • Bronchiolitis Obliterans / epidemiology
  • Bronchiolitis Obliterans / microbiology*
  • Bronchiolitis Obliterans / therapy
  • Humans
  • Respiratory Function Tests
  • Risk Factors
  • South America