Pediatric heart allocation and transplantation in Eurotransplant

Transpl Int. 2014 Sep;27(9):917-25. doi: 10.1111/tri.12356. Epub 2014 Jun 23.

Abstract

Pediatric heart allocation in Eurotransplant (ET) has evolved over the past decades to better serve patients and improve utilization. Pediatric heart transplants (HT) account for 6% of the annual transplant volume in ET. Death rates on the pediatric heart transplant waiting list have decreased over the years, from 25% in 1997 to 18% in 2011. Within the first year after listing, 32% of all infants (<12 months), 20% of all children aged 1-10 years, and 15% of all children aged 11-15 years died without having received a heart transplant. Survival after transplantation improved over the years, and in almost a decade, the 1-year survival went from 83% to 89%, and the 3-year rates increased from 81% to 85%. Improved medical management of heart failure patients and the availability of mechanical support for children have significantly improved the prospects for children on the heart transplant waiting list.

Keywords: heart transplant survival; organ donation; pediatric transplantation; wait list mortality.

MeSH terms

  • Adolescent
  • Age Determination by Skeleton
  • Child
  • Child, Preschool
  • Europe
  • Follow-Up Studies
  • Health Policy
  • Heart Diseases / mortality
  • Heart Diseases / surgery
  • Heart Transplantation / mortality
  • Heart Transplantation / statistics & numerical data*
  • Heart-Assist Devices
  • Humans
  • Infant
  • Kaplan-Meier Estimate
  • Tissue Donors / supply & distribution
  • Tissue and Organ Procurement / organization & administration
  • Tissue and Organ Procurement / standards
  • Tissue and Organ Procurement / statistics & numerical data*
  • Transplant Recipients / classification
  • Transplant Recipients / statistics & numerical data
  • Treatment Outcome
  • Waiting Lists* / mortality