Risk factors of early and late mortality after thoracic endovascular aortic repair for complicated stanford B acute aortic dissection

J Card Surg. 2014 Jul;29(4):501-6. doi: 10.1111/jocs.12377. Epub 2014 May 26.

Abstract

Background and aim of the study: The risk factors associated with death in complicated Stanford B acute aortic dissection (AAD) after thoracic endovascular aortic repair (TEVAR) are poorly understood. The aim of this study was to evaluate the early and late events and mortality of complicated Stanford B AAD associated with TEVAR.

Methods: Sixty-two patients with complicated Stanford B AAD undergoing TEVAR were included in this study.

Results: Primary technical success of TEVAR was achieved in 61 (98.39%) cases. The early mortality rate was 9.68%. Procedural type I endoleak (p = 0.007, OR = 7.71, 95% CI: 1.75-34.01) and cardiac tamponade (p = 0.010, OR = 8.86, 95% CI: 1.70-4 6.14) were the significant predictors of early death in the multivariate model. The late mortality was 16.07%. Cox regression analysis revealed rupture of false lumen (p = 0.001, hazard ratio = 21.96, 95% CI: 3.02-82.12), postoperative myocardial infarction (p = 0.001, hazard ratio = 9.86, 95% CI: 2.12-39.64), and acute renal failure (p = 0.024, hazard ratio = 3.98, 95% CI: 1.26-12.11) to be independent risk factors of late mortality.

Conclusions: Type I procedural endoleak and cardiac tamponade were the significant predictors of early death in patients of complicated Stanford B AAD undergoing TEVAR. Rupture of false lumen, postoperative myocardial infarction, and acute renal failure were the independent risk factors for late death after TEVAR.

MeSH terms

  • Acute Disease
  • Acute Kidney Injury
  • Aged
  • Aortic Aneurysm / mortality*
  • Aortic Aneurysm / surgery*
  • Aortic Dissection / mortality*
  • Aortic Dissection / surgery*
  • Cardiac Tamponade
  • Endoleak
  • Endovascular Procedures / methods*
  • Endovascular Procedures / mortality*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Myocardial Infarction
  • Postoperative Complications*
  • Proportional Hazards Models
  • Risk Factors
  • Thoracic Surgical Procedures / methods*
  • Time Factors
  • Treatment Outcome