Treatment of malignant gliomas in elderly patients: a concise overview of the literature

Biomed Res Int. 2014:2014:734281. doi: 10.1155/2014/734281. Epub 2014 Apr 22.

Abstract

Gliomas are the most frequent primary brain tumors and the incidence data has increased in the elderly population. Unfortunately, prospective studies on this population are few and so the right treatment is unknown. In the elderly patients no standard treatment has been established and therefore the optimal treatment should be individualized. We performed a review analyzing the prognostic and predictive factors, the clinical studies, and the correct management of this population.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Brain Neoplasms / epidemiology
  • Brain Neoplasms / genetics
  • Brain Neoplasms / physiopathology
  • Brain Neoplasms / therapy*
  • Cognition
  • Glioma / epidemiology
  • Glioma / genetics
  • Glioma / physiopathology
  • Glioma / therapy*
  • Humans
  • Prognosis
  • Quality of Life