Exploring new models of easiRNA biogenesis

Nat Genet. 2014 Jun;46(6):530-1. doi: 10.1038/ng.2993.

Abstract

Although silent transposons in plants can be reactivated by stress or during development, their potential deleterious effects are prevented by transposon-derived epigenetically activated small interfering RNAs (easiRNAs). A new study shows how serendipitous interactions between reactivated transposons and endogenous microRNAs might initiate easiRNA biogenesis, establishing an unexpected link between these two classes of silencing small RNAs.

Publication types

  • Comment

MeSH terms

  • Arabidopsis / genetics*
  • Epigenesis, Genetic*
  • MicroRNAs / genetics*
  • RNA, Small Interfering / genetics*
  • Retroelements / genetics*

Substances

  • MicroRNAs
  • RNA, Small Interfering
  • Retroelements