Pain relief from combined wound and intraperitoneal local anesthesia for patients who undergo laparoscopic cholecystectomy

BMC Surg. 2014 May 12:14:28. doi: 10.1186/1471-2482-14-28.

Abstract

Background: Laparoscopic cholecystectomy (LC) has become the treatment of choice for gallbladder lesions, but it is not a pain-free procedure. This study explored the pain relief provided by combined wound and intraperitoneal local anesthetic use for patients who are undergoing LC.

Methods: Two-hundred and twenty consecutive patients undergoing LC were categorized into 1 of the following 4 groups: local wound anesthetic after LC either with an intraperitoneal local anesthetic (W + P) (group 1) or without an intraperitoneal local anesthetic (W + NP) (group 2), or no local wound anesthetic after LC either with intraperitoneal local anesthetic (NW + P) (group 3) or without an intraperitoneal local anesthetic (NW + NP) (group 4). A visual analog scale (VAS) was used to assess postoperative pain. The amount of analgesic used and the duration of hospital stay were also recorded.

Results: The VAS was significantly lower immediately after LC for the W + P group than for the NW + NP group (5 vs. 6; p = 0.012). Patients in the W + P group received a lower total amount of meperidine during their hospital stay. They also had the shortest hospital stay after LC, compared to the patients in the other groups.

Conclusion: Combined wound and intraperitoneal local anesthetic use after LC significantly decreased the immediate postoperative pain and may explain the reduced use of meperidine and earlier discharge of patients so treated.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Administration, Topical
  • Adult
  • Aged
  • Aged, 80 and over
  • Amides / administration & dosage*
  • Amides / therapeutic use
  • Anesthesia, Local / methods*
  • Anesthetics, Local / administration & dosage*
  • Anesthetics, Local / therapeutic use
  • Cholecystectomy, Laparoscopic*
  • Drug Administration Schedule
  • Female
  • Humans
  • Infusions, Parenteral
  • Male
  • Middle Aged
  • Pain Measurement
  • Pain, Postoperative / prevention & control*
  • Prospective Studies
  • Ropivacaine
  • Treatment Outcome

Substances

  • Amides
  • Anesthetics, Local
  • Ropivacaine