Intra-operative guidance: methods for achieving negative margins in breast conserving surgery

J Surg Oncol. 2014 Jul;110(1):21-5. doi: 10.1002/jso.23645. Epub 2014 May 29.

Abstract

The increasing incidence of breast cancer and advances in detection of small, impalpable cancers presents increasing challenges for the modern breast surgeon. Accurate localization and excision with adequate oncological margins to reduce loco-regional recurrence rates whilst minimizing volume deficit and maximizing aesthetics remains the "gold standard." We review the current techniques available and the developments within this field.

Keywords: localization; margins; subclinical breast cancer.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery*
  • Female
  • Humans
  • Intraoperative Care*
  • Mastectomy, Segmental / methods*
  • Mastectomy, Segmental / standards*