Circulating MicroRNAs in gynecological malignancies: from detection to prediction

Exp Hematol Oncol. 2014 May 20:3:14. doi: 10.1186/2162-3619-3-14. eCollection 2014.

Abstract

MicroRNAs (miRNAs) have been demonstrated to play critical roles in many physiological and pathophysiological processes. The presence of altered miRNA profiles in human body fluids has been reported for a number of diseases including gynecological malignancies. In this review, we summarized the current progresses of circulating miRNAs associated with malignancies in gynecology, with an emphasizing on the circulating miRNAs as diagnostic and prognostic biomarkers in ovarian cancer, endometrial carcinoma and cervical cancer.

Publication types

  • Review