Bioinformatic analyses of CALR mutations in myeloproliferative neoplasms support a role in signaling

Leukemia. 2014 Oct;28(10):2106-9. doi: 10.1038/leu.2014.190. Epub 2014 Jun 12.

Authors

L Eder-Azanza¹, D Navarro¹, P Aranaz¹, F J Novo¹, N C P Cross², J L Vizmanos¹

Affiliations

¹ Department of Biochemistry & Genetics, School of Science, University of Navarra, Pamplona, Spain.
² 1] Wessex Regional Genetics Laboratory, Salisbury NHS Foundation Trust, Salisbury District Hospital, Salisbury, UK [2] Faculty of Medicine, University of Southampton, Southampton, UK.

PMID: 24919806
DOI: 10.1038/leu.2014.190

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Algorithms
Animals
Calreticulin / genetics*
Calreticulin / physiology
Computational Biology
Exons
Humans
Mice
Mutation
Myeloproliferative Disorders / genetics*
Phosphorylation
Protein Folding
Protein Structure, Tertiary
STAT3 Transcription Factor / metabolism
Signal Transduction*
Software

Substances

Calreticulin
STAT3 Transcription Factor
STAT3 protein, human