Pain in Sjögren's syndrome

Reumatismo. 2014 Jun 6;66(1):39-43. doi: 10.4081/reumatismo.2014.763.

Abstract

Sjögren's syndrome (SjS) is an autoimmune disease that affects the salivary and lacrimal glands, but it can also have extra-glandular manifestations. Although pain has not yet been fully studied and characterized, it is a symptom that can be often found in patients with SjS, who mainly complain of neuropathic pain, followed by nociceptive pain. The latter when combined with widespread dysfunctional symptoms is defined fibromyalgia. The aim of this work is to analyze the scientific literature on the presence of pain in patients with primary Sjögren's syndrome.

Publication types

  • Review

MeSH terms

  • Analgesics / therapeutic use
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Central Nervous System Sensitization
  • Combined Modality Therapy
  • Comorbidity
  • Exercise Therapy
  • Fatigue / etiology
  • Fibromyalgia / diagnosis
  • Fibromyalgia / etiology
  • Fibromyalgia / physiopathology
  • Humans
  • Neurotransmitter Agents / physiology
  • Nociception / physiology
  • Pain / drug therapy
  • Pain / etiology*
  • Pain / physiopathology
  • Pain / psychology
  • Pain Management
  • Pain Perception
  • Sjogren's Syndrome / immunology
  • Sjogren's Syndrome / physiopathology*

Substances

  • Analgesics
  • Anti-Inflammatory Agents, Non-Steroidal
  • Neurotransmitter Agents