Fetal programming by high-sucrose diet during pregnancy affects the vascular angiotensin II receptor-PKC-L-type Ca(2+) channels (Cav1.2) axis to enhance pressor responses

Hypertens Res. 2014 Sep;37(9):796-8. doi: 10.1038/hr.2014.105. Epub 2014 Jun 19.

Authors

Kouichi Tamura¹, Koji Ohki¹, Ryu Kobayashi¹, Kazushi Uneda¹, Kengo Azushima¹, Masato Ohsawa¹, Hiromichi Wakui¹, Satoshi Umemura¹

Affiliation

¹ Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

PMID: 24942769
DOI: 10.1038/hr.2014.105

No abstract available

Publication types

Comment

MeSH terms

Angiotensin II / pharmacology*
Animals
Blood Pressure / drug effects*
Calcium Channels, L-Type / metabolism*
Dietary Sucrose*
Female
Microvessels / drug effects*
Pregnancy
Prenatal Exposure Delayed Effects / metabolism*
Protein Kinase C / metabolism*
Signal Transduction / drug effects*

Substances

Calcium Channels, L-Type
Dietary Sucrose
L-type calcium channel alpha(1C)
Angiotensin II
Protein Kinase C