Abstract
A Pd(II)-catalyzed arylation of methylene C(sp(3))-H bonds in aliphatic amides directed by our newly developed PIP directing group with aryl iodides/bromides has been achieved. Arylation occurs efficiently with a broad range of aryl halides and amides.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amides / chemistry
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Bromides / chemistry
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Carbon / chemistry
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Catalysis
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Hydrogen / chemistry
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Iodides / chemistry
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Palladium / chemistry*
Substances
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Amides
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Bromides
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Iodides
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Palladium
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Carbon
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Hydrogen