Preliminary crystallographic data for NAD(P)H quinone reductase isolated from the Walker 256 rat carcinoma cell line

J V Skelly; D A Suter; R J Knox; E Garman; D I Stuart; M R Sanderson; J J Roberts; S Neidle

doi:10.1016/0022-2836(89)90233-7

Preliminary crystallographic data for NAD(P)H quinone reductase isolated from the Walker 256 rat carcinoma cell line

J Mol Biol. 1989 Feb 5;205(3):623-4. doi: 10.1016/0022-2836(89)90233-7.

Authors

J V Skelly¹, D A Suter, R J Knox, E Garman, D I Stuart, M R Sanderson, J J Roberts, S Neidle

Affiliation

¹ CRC Biomolecular Structure Unit, Institute of Cancer Research, Sutton, Surrey, U.K.

PMID: 2494346
DOI: 10.1016/0022-2836(89)90233-7

Abstract

An NAD(P)H quinone reductase isolated from Walker rat 256 carcinoma cells has been crystallized in a form suitable for high-resolution structural analysis. The crystals belong to orthorhombic space group P2(1)2(1)2(1) with cell parameters a = 168.15 A, b = 105.09 A and c = 67.38 A and contain four monomeric or two dimeric enzyme molecules per asymmetric unit. Diffraction extends beyond 2.3 A resolution.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Line
NAD(P)H Dehydrogenase (Quinone)
Quinone Reductases*
Rats
Tumor Cells, Cultured / enzymology
X-Ray Diffraction

Substances

NAD(P)H Dehydrogenase (Quinone)
Quinone Reductases