Palladium-catalyzed thiolation of alkanes and ethers with arylsulfonyl hydrazides

Chem Commun (Camb). 2014 Aug 11;50(62):8578-81. doi: 10.1039/c4cc02876g.

Abstract

A new method for the preparation of alkyl aryl sulfides through direct oxidative thiolation of alkanes or ethers with arylsulfonyl hydrazides using di-tert-butyl peroxide (DTBP) as an oxidant catalyzed by Pd(OAc)2 has been reported. The C-H bonds in various alkanes or ethers were successfully converted into C-S bonds to yield the corresponding sulfides in moderate to good yields.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkanes / chemistry*
  • Catalysis
  • Ethers / chemistry*
  • Molecular Structure
  • Palladium / chemistry*
  • Peroxides / chemistry*
  • Sulfides / chemical synthesis*

Substances

  • Alkanes
  • Ethers
  • Peroxides
  • Sulfides
  • di-tert-butyl peroxide
  • Palladium