Chemotherapy-associated hepatotoxicity in colorectal cancer

J BUON. 2014 Apr-Jun;19(2):350-6.

Abstract

Chemotherapy-associated hepatotoxicity in liver metastatic colorectal cancer is attracting more and more attention for clinicians. This hepatotoxicity heralds an increased risk of morbidity and mortality in patients with colorectal liver metastases, therefore it is important that clinicians have an adequate knowledge of the chemotherapy-associated hepatotoxicity.

Publication types

  • Review

MeSH terms

  • Camptothecin / adverse effects
  • Camptothecin / analogs & derivatives
  • Chemical and Drug Induced Liver Injury / diagnosis
  • Chemical and Drug Induced Liver Injury / etiology*
  • Colorectal Neoplasms / drug therapy*
  • Fatty Liver / chemically induced
  • Fluorouracil / adverse effects
  • Humans
  • Irinotecan
  • Non-alcoholic Fatty Liver Disease

Substances

  • Irinotecan
  • Fluorouracil
  • Camptothecin