The prostate cancer foundation (PCF) is committed to the facilitation of global knowledge exchange as a mechanism for more rapidly discovering and developing new medicines and treatments for prostate cancer (PCa) patients worldwide. For the past 3 years, PCF has partnered with the Chinese Prostate Cancer Consortium and Shanghai Changhai Hospital to host a conference in China that brings together basic, translational, and clinical researchers from China and abroad to form new partnerships and exchange findings, insights, perspectives, and ideas toward improving the treatment of PCa. The seventh forum of prostate disease held in Shanghai, China, on July 26–28, 2013, focused on current and emerging developments and approaches in PCa diagnosis, prognosis, and treatment, and the discovery and targeting of disease mechanisms that drive metastasis and lethal subtypes of castrate-resistant PCa (CRPC). This special edition of the Asian Journal of Andrology highlights some of the most pressing topics that were presented and discussed at the forum.