Quaternized carbon dot-modified graphene oxide for selective cell labelling--controlled nucleus and cytoplasm imaging

K K R Datta; O Kozák; V Ranc; M Havrdová; A B Bourlinos; K Safářová; K Holá; K Tománková; G Zoppellaro; M Otyepka; R Zbořil

doi:10.1039/c4cc02637c

Quaternized carbon dot-modified graphene oxide for selective cell labelling--controlled nucleus and cytoplasm imaging

Chem Commun (Camb). 2014 Sep 25;50(74):10782-5. doi: 10.1039/c4cc02637c.

Authors

K K R Datta¹, O Kozák, V Ranc, M Havrdová, A B Bourlinos, K Safářová, K Holá, K Tománková, G Zoppellaro, M Otyepka, R Zbořil

Affiliation

¹ Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacky University in Olomouc, Slechtitelu 11, 78371 Olomouc, Czech Republic. [email protected].

PMID: 24983507
DOI: 10.1039/c4cc02637c

Abstract

Cationic quaternized carbon dots (QCDs) and anionic graphene oxide sheets (GO) are combined via non-covalent interactions following a self-assembly pathway to form highly biocompatible and fluorescent hybrid materials. These hybrids act as selective probes with controlled labelling of the cell nucleus or cytoplasm depending on the QCD loading.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Carbon / chemistry*
Cations / chemistry
Cell Nucleus / chemistry
Cell Nucleus / metabolism
Cytoplasm / chemistry
Cytoplasm / metabolism
Graphite / chemistry*
Mice
Microscopy, Confocal
NIH 3T3 Cells
Oxides / chemistry
Quantum Dots / chemistry*
Quantum Dots / metabolism

Substances

Cations
Oxides
Carbon
Graphite