Incidence of deferasirox-associated renal tubular dysfunction in children and young adults with beta-thalassaemia

Br J Haematol. 2014 Nov;167(3):434-6. doi: 10.1111/bjh.13002. Epub 2014 Jul 2.
No abstract available

Keywords: deferasirox; iron overload; renal tubular dysfunction; serum electrolyte; β-thalassaemia.

Publication types

  • Letter

MeSH terms

  • Adolescent
  • Alkalosis / chemically induced
  • Benzoates / adverse effects*
  • Benzoates / therapeutic use
  • Chelation Therapy / adverse effects*
  • Child
  • Child, Preschool
  • Deferasirox
  • Deferiprone
  • Deferoxamine / therapeutic use
  • Fanconi Syndrome / chemically induced
  • Female
  • Humans
  • Iron Chelating Agents / adverse effects*
  • Iron Chelating Agents / therapeutic use
  • Kidney Diseases / chemically induced*
  • Kidney Tubules / drug effects
  • Kidney Tubules / physiopathology
  • Male
  • Pyridones / therapeutic use
  • Retrospective Studies
  • Transfusion Reaction
  • Triazoles / adverse effects*
  • Triazoles / therapeutic use
  • Water-Electrolyte Imbalance / chemically induced
  • Young Adult
  • beta 2-Microglobulin / analysis
  • beta-Thalassemia / complications*
  • beta-Thalassemia / drug therapy
  • beta-Thalassemia / therapy

Substances

  • Benzoates
  • Iron Chelating Agents
  • Pyridones
  • Triazoles
  • beta 2-Microglobulin
  • Deferiprone
  • Deferoxamine
  • Deferasirox