Focused low-energy extracorporeal shock waves with distally symmetric polyneuropathy (DSPNP): a pilot study

NeuroRehabilitation. 2014 Jan 1;35(2):227-33. doi: 10.3233/NRE-141116.

Abstract

Background: Incidental observations led to the question whether ESWT could alleviate the still difficult-to-improve symptoms of DSPNP.

Methods: In a pilot study, out of an original 24 patients with DSPNP, 10 patients with diabetes mellitus were excluded because of their inhomogeneous performances. Of the 14 patients remaining, 6 received one sham treatment at the beginning. All 14 patients were then treated with ESWT to the soles of the feet using the Duolith® shock wave generator (Storz Medical) 3 times weekly for 2 weeks. The assessments were carried out before and after the sham treatment, the first ESWT (question: before and after the first ESWT or only after?) and after 2, 4 and 8 weeks.

Results: The placebo treatment did not influence pain or paraesthesia. After the 2 weeks of ESWT, intensity decreased from 100% to 23.6%, rising again after 8 weeks to 45.7% of the original state (p < 0.01). The placebo treatment did however have a great effect on walking abilities. The results of ESWT did not become significant until the 8th week. Step length improved by 14.6% (p < 0.001), walking speed by 24.8% (p < 0.001) and time of dual support during the stance phase of the gait declined by 12.2% (p < 0.009).

Conclusions: Despite the small number of cases, it appears that ESWT can alleviate some of the symptoms of DSPNP.

Keywords: Extracorporeal shock wave therapy; pain; paraesthesia; polyneuropathy; walking kinematics.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biomechanical Phenomena
  • Female
  • Foot Diseases / rehabilitation*
  • Gait
  • High-Energy Shock Waves / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Pain / etiology
  • Pain / prevention & control
  • Pilot Projects
  • Placebos
  • Polyneuropathies / complications
  • Polyneuropathies / rehabilitation*
  • Recovery of Function
  • Treatment Outcome

Substances

  • Placebos