Seeing is believing: new methods for in situ single-cell transcriptomics

Genome Biol. 2014 Mar 31;15(3):110. doi: 10.1186/gb4169.

Abstract

New methods employ RNA-seq to study single cells within complex tissues by in situ sequencing or mRNA capture from single photoactivated cells.

Publication types

  • Review
  • Comment

MeSH terms

  • Animals
  • Brain / metabolism*
  • Gene Expression Profiling / methods*
  • High-Throughput Nucleotide Sequencing / methods*
  • Hippocampus / metabolism*
  • Humans
  • Neurons / metabolism*
  • Sequence Analysis, RNA / methods*
  • Transcriptome*