[Demarcation of infection with Salmonella typhi and S. paratyphi against Salmonella enteritidis in children]

Klin Padiatr. 2014 Jul;226(4):238-42. doi: 10.1055/s-0034-1375698. Epub 2014 Jul 10.
[Article in German]

Abstract

Background: Typhoid and paratyphoid infections (STP) are an important differential diagnosis for Salmonella enteritidis infections (NTS). The aim of this study is to carve out clinical differences between both infections.

Patients/methods: We retrospectively reviewed all patients admitted to our hospital between 2007 and 2011 with a diagnosis of STP infection. History, clinical course and laboratory findings were compared with age-matched patients suffering from NTS.

Results/discussion: All patients with an STP-infection showed had a positive travel history (as compared to 11.1% in the NTS group, p<0.01). Salmonella were mostly isolated from blood cultures (n=7/9) in the STP group as compared to 1/16 in the NTS group, where S. enteridis was mainly isolated from faecal cultures (p<0,01). The duration and height of fever as well as the time of hospitalization were significantly longer with STP infections than with NTS infections. Eosinopenia was observed both in STP-(100%) and NTS-infections (77.8%).

Conclusion: A positive travel history is crucial to the identification of a STP infection, as well as an eosinopenia.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Bacteriological Techniques
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Paratyphoid Fever / diagnosis*
  • Paratyphoid Fever / transmission
  • Predictive Value of Tests
  • Retrospective Studies
  • Salmonella Infections / diagnosis*
  • Salmonella Infections / microbiology
  • Salmonella Infections / transmission
  • Salmonella enteritidis*
  • Salmonella paratyphi A*
  • Salmonella typhi*
  • Travel
  • Typhoid Fever / diagnosis*
  • Typhoid Fever / microbiology
  • Typhoid Fever / transmission