Abstract
Human papillomavirus (HPV)-associated oropharyngeal carcinoma is now recognized as a clinically distinct subtype of head and neck cancer with important prognostic implications. HPV testing is recommended as the standard of care for all patients diagnosed with oropharyngeal squamous cell carcinoma. Here, we describe a practical approach to HPV testing within the setting of the diagnostic histopathology laboratory.
MeSH terms
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Algorithms
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Carcinoma, Squamous Cell / diagnosis*
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Carcinoma, Squamous Cell / pathology
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Carcinoma, Squamous Cell / virology*
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DNA, Viral / genetics
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Head and Neck Neoplasms / diagnosis*
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Head and Neck Neoplasms / pathology
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Head and Neck Neoplasms / virology*
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Humans
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Immunohistochemistry
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In Situ Hybridization
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Papillomaviridae / genetics
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Papillomaviridae / isolation & purification*
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Papillomaviridae / physiology*
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Polymerase Chain Reaction
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Risk
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Squamous Cell Carcinoma of Head and Neck