Renal dysfunction in end-stage liver disease and post-liver transplant

Marcelo S Sampaio; Paul Martin; Suphamai Bunnapradist

doi:10.1016/j.cld.2014.05.003

Renal dysfunction in end-stage liver disease and post-liver transplant

Clin Liver Dis. 2014 Aug;18(3):543-60. doi: 10.1016/j.cld.2014.05.003.

Authors

Marcelo S Sampaio¹, Paul Martin², Suphamai Bunnapradist³

Affiliations

¹ Division of Nephrology, Department of Medicine, Kidney and Pancreas Transplant Program, David Geffen School of Medicine at UCLA, 1015 Gayley Avenue, Suite 220, Los Angeles, CA 90024, USA.
² Division of Hepatology, Miller School of Medicine, University of Miami, 1500 NW 12 Avenue, Jackson Medical Tower E-1101, Miami, FL 33136, USA.
³ Division of Nephrology, Department of Medicine, Kidney and Pancreas Transplant Program, David Geffen School of Medicine at UCLA, 1015 Gayley Avenue, Suite 220, Los Angeles, CA 90024, USA. Electronic address: [email protected].

PMID: 25017075
DOI: 10.1016/j.cld.2014.05.003

Abstract

Renal dysfunction is a frequent complication in patients with end-stage liver disease awaiting orthotopic liver transplantation and in the post-liver transplant period. Although the stereotypical form of renal dysfunction is the hepatorenal syndrome, other causes of acute kidney injury in this population include prerenal azotemia and acute tubular necrosis. Renal injury in a patient with cirrhosis is associated with a poor prognosis.

Keywords: Liver transplant; Liver-kidney transplant; Renal failure.

Publication types

Review

MeSH terms

Azotemia / complications
End Stage Liver Disease / complications*
End Stage Liver Disease / surgery*
Hepatorenal Syndrome / complications
Humans
Kidney Function Tests
Kidney Transplantation
Liver Cirrhosis / complications
Liver Transplantation / adverse effects*
Patient Selection
Postoperative Complications / therapy
Renal Insufficiency / complications*
Renal Insufficiency / etiology
Renal Insufficiency / therapy
Renal Replacement Therapy