[Autologous stem cell transplantation for autoimmune diseases: recommendations from the SFGM-TC]

D Farge; L Terriou; M Badoglio; A Cras; P Desreumaux; S Hadj-Khelifa; Z Marjanovic; A Moisan; R Dulery; C Faucher; A Hij; T Martin; P Vermersch; I Yakoub-Agha; SFGM-TC

doi:10.1016/j.patbio.2014.05.012

[Autologous stem cell transplantation for autoimmune diseases: recommendations from the SFGM-TC]

Pathol Biol (Paris). 2014 Aug;62(4):204-8. doi: 10.1016/j.patbio.2014.05.012. Epub 2014 Jul 10.

[Article in French]

Authors

D Farge¹, L Terriou², M Badoglio³, A Cras⁴, P Desreumaux⁵, S Hadj-Khelifa⁶, Z Marjanovic⁷, A Moisan⁸, R Dulery², C Faucher⁹, A Hij⁶, T Martin¹⁰, P Vermersch¹¹, I Yakoub-Agha²; SFGM-TC

Affiliations

¹ Unité de médecine interne et pathologie vasculaire, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75475 Paris, France. Electronic address: [email protected].
² Maladies du sang, CHRU de Lille, rue Michel-Polonovski, 59037 Lille cedex, France.
³ EBMT Data Office, hôpital Saint-Antoine, 184, rue du Faubourg Saint-Antoine, 75571 Paris cedex 12, France.
⁴ Unité de thérapie cellulaire et CIC-BT, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France.
⁵ Service des maladies de l'appareil digestif et de la nutrition, hôpital Claude-Huriez, CHU de Lille, 59037 Lille, France.
⁶ Unité de médecine interne et pathologie vasculaire, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75475 Paris, France.
⁷ Hématologie clinique et thérapie cellulaire, hôpital Saint-Antoine, AP-HP, 184, rue du Faubourg Saint-Antoine, 75571 Paris cedex 12, France.
⁸ Inserm U836, Grenoble institut des neurosciences, université Joseph-Fourier, chemin Fortuné-Ferrini, 38706 Grenoble, France.
⁹ Direction médicale et scientifique, agence de la biomédecine, 1, avenue du stade-de-France, 93212 Saint-Denis, France.
¹⁰ Service de médecine interne et immunologie clinique, hôpital Civil, 1, place de l'hôpital BP 426, 67091 Strasbourg cedex, France.
¹¹ Service de neurologie générale et pathologie neuro-inflammatoire, CHRU de Lille, 2, avenue Oscar-Lambret, 59037 Lille cedex, France.

PMID: 25017794
DOI: 10.1016/j.patbio.2014.05.012

Abstract

Autologous hematopoietic stem cell transplantation is a valid alternative to immunosuppressive treatment in patients with auto-immune disease; however, the role of this approach remains subject to debate. In the attempt to harmonize clinical practices between different French transplantation centers, the French Society of Bone Marrow Transplantation and Cell Therapies (SFGM-TC) set up its fourth annual series of workshops which brought together practitioners from all of its member centers. These workshops took place in September 2013 in Lille. In this article we give an overview regarding the indications of autologous stem cell transplantation in auto-immune diseases as well as recommendations regarding post-transplant follow-up of patients.

Keywords: Auto-immune disease; Autogreffe; Autologous stem cell transplantation; Indications; Maladies auto-immunes.

Publication types

English Abstract
Practice Guideline
Research Support, Non-U.S. Gov't

MeSH terms

Autoimmune Diseases / surgery*
France
Humans
Immunosuppressive Agents
Postoperative Care
Stem Cell Transplantation / adverse effects
Stem Cell Transplantation / methods*
Stem Cell Transplantation / standards
Transplantation, Autologous / adverse effects
Transplantation, Autologous / methods*
Transplantation, Autologous / standards

Substances

Immunosuppressive Agents