In vitro conversion of morphine to 6-acetylmorphine in urine samples during enzymatic hydrolysis

Clin Chem. 2014 Sep;60(9):1234-5. doi: 10.1373/clinchem.2014.226720. Epub 2014 Jul 14.

Authors

Courtney Heideloff¹, Jessica Gabler², Chao Yuan¹, Lin Zhang³, Sihe Wang⁴

Affiliations

¹ Department of Laboratory Medicine, Cleveland Clinic Cleveland, OH.
² Unity Lab Services Thermo Fisher Scientific West Palm Beach, FL.
³ Department of Chemistry Cleveland State University Cleveland, OH.
⁴ Department of Laboratory Medicine, Cleveland Clinic Cleveland, OH Department of Chemistry Cleveland State University Cleveland, OH [email protected].

PMID: 25024270
DOI: 10.1373/clinchem.2014.226720

No abstract available

Publication types

Letter

MeSH terms

False Positive Reactions
Humans
Hydrolysis
Morphine / metabolism*
Morphine / urine
Morphine Derivatives / urine*
Urinalysis / standards*
beta-Glucosidase / metabolism

Substances

Morphine Derivatives
Morphine
beta-Glucosidase
6-O-monoacetylmorphine