Abstract
From the thermoacidophilic archaebacterium, Thermoplasma acidophilum, a proteolytically active particle has been isolated which is almost identical in size and shape with the multicatalytic proteinase (prosome) from rat. This result indicates that prosomes have been developed early in evolution and that they possibly serve functions common to all living cells.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Archaea / enzymology*
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Bacteria / enzymology*
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Biological Evolution
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Calcium Chloride / pharmacology
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Chromatography
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Cysteine Endopeptidases / isolation & purification*
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Cysteine Endopeptidases / metabolism
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Electrophoresis, Polyacrylamide Gel
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Macromolecular Substances
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Microscopy, Electron
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Molecular Weight
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Multienzyme Complexes / isolation & purification*
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Multienzyme Complexes / metabolism
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Muscles / enzymology
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Peptide Fragments
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Proteasome Endopeptidase Complex
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Rats
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Substrate Specificity
Substances
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Macromolecular Substances
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Multienzyme Complexes
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Peptide Fragments
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Cysteine Endopeptidases
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Proteasome Endopeptidase Complex
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Calcium Chloride