Simultaneous lupus anticoagulant and anticardiolipin assays and clinical detection of antiphospholipids

M H Rosove; P M Brewer; A Runge; K Hirji

doi:10.1002/ajh.2830320215

Simultaneous lupus anticoagulant and anticardiolipin assays and clinical detection of antiphospholipids

Am J Hematol. 1989 Oct;32(2):148-9. doi: 10.1002/ajh.2830320215.

Authors

M H Rosove¹, P M Brewer, A Runge, K Hirji

Affiliation

¹ Department of Medicine, University of California, Los Angeles 90024.

PMID: 2502915
DOI: 10.1002/ajh.2830320215

Abstract

Lupus anticoagulants and/or anticardiolipin antibodies were detected in 100 patients with autoimmune disorders, thrombosis, or pregnancy loss. Significant agreement between tests for these two antiphospholipid activities was lacking. Performing both assays is thus important in maximizing the likelihood of detecting antiphospholipids that may have clinical relevance.

MeSH terms

Abortion, Spontaneous / immunology
Autoantibodies / analysis*
Autoimmune Diseases / immunology
Blood Coagulation Factors / analysis
Blood Coagulation Factors / immunology*
Cardiolipins / immunology*
Female
Humans
Lupus Coagulation Inhibitor
Pregnancy
Thrombosis / immunology

Substances

Autoantibodies
Blood Coagulation Factors
Cardiolipins
Lupus Coagulation Inhibitor