Fluorocholine PET/computed tomography: physiologic uptake, benign findings, and pitfalls

Mohsen Beheshti; Athar Haroon; Jamshed B Bomanji; Werner Langsteger

doi:10.1016/j.cpet.2014.03.001

Fluorocholine PET/computed tomography: physiologic uptake, benign findings, and pitfalls

PET Clin. 2014 Jul;9(3):299-306. doi: 10.1016/j.cpet.2014.03.001. Epub 2014 Apr 22.

Authors

Mohsen Beheshti¹, Athar Haroon², Jamshed B Bomanji², Werner Langsteger³

Affiliations

¹ PET-CT Center LINZ, Department of Nuclear Medicine and Endocrinology, St. Vincent's Hospital, Seilerstaette 4, Linz A-4020, Austria. Electronic address: [email protected].
² T5 University College London Hospital, London, UK.
³ PET-CT Center LINZ, Department of Nuclear Medicine and Endocrinology, St. Vincent's Hospital, Seilerstaette 4, Linz A-4020, Austria.

PMID: 25030393
DOI: 10.1016/j.cpet.2014.03.001

Abstract

Choline PET has a role in the diagnosis of malignancies. Knowledge of normal biodistribution plays a vital role in disease characterization and in differentiating normal variants from disease processes. CT and MR scans provide complementary information, and choline-positive sites should be correlated clinically to exclude inflammatory disorders.

Keywords: Benign findings; Choline; PET/CT; Physiologic variation; Pitfalls.

Publication types

Review

MeSH terms

Abdomen / diagnostic imaging
Central Nervous System / diagnostic imaging
Choline / analogs & derivatives*
Choline / pharmacokinetics
Contraindications
Fluorine Radioisotopes / pharmacokinetics*
Humans
Neoplasms / diagnostic imaging
Positron-Emission Tomography / methods*
Radiopharmaceuticals / pharmacokinetics*
Thorax / diagnostic imaging
Tissue Distribution
Tomography, X-Ray Computed / methods*
Urogenital System / diagnostic imaging

Substances

Fluorine Radioisotopes
Radiopharmaceuticals
fluorocholine
Choline