Pleural solitary fibrous tumor complicated with autoimmune hemolytic anemia

Intern Med. 2014;53(14):1549-52. doi: 10.2169/internalmedicine.53.2121. Epub 2014 Jul 15.

Abstract

We herein report a 74-year-old woman who presented with autoimmune hemolytic anemia (AIHA) associated with pleural solitary fibrous tumor (SFT). Her AIHA was initially treated with 1 mg/kg daily of oral prednisolone (PSL) for 2 months, which had a limited effect. However, after surgical tumor resection, the patient showed remarkable improvement of AIHA with normalizations of serum lactate dehydrogenase and bilirubin levels, and we were able to rapidly reduce the PSL dosage. This is the first description of a case of AIHA caused by SFT.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Aged
  • Anemia, Hemolytic, Autoimmune / diagnosis
  • Anemia, Hemolytic, Autoimmune / drug therapy
  • Anemia, Hemolytic, Autoimmune / etiology*
  • Diagnosis, Differential
  • Dose-Response Relationship, Drug
  • Female
  • Glucocorticoids / administration & dosage
  • Humans
  • Prednisolone / administration & dosage*
  • Radiography, Thoracic
  • Solitary Fibrous Tumor, Pleural / complications*
  • Solitary Fibrous Tumor, Pleural / diagnosis
  • Solitary Fibrous Tumor, Pleural / surgery
  • Thoracic Surgical Procedures / methods
  • Tomography, X-Ray Computed

Substances

  • Glucocorticoids
  • Prednisolone