[The role of CD4+CD25+ regulatory T cells in helminth infection immunity]

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2014 Apr;32(2):148-51.
[Article in Chinese]

Abstract

Regulatory T cells (Tregs), a class of CD4+ T lymphocytes which are different from the Th1 and Th2 lymphocytes, have immunosuppressive function and play an important role in maintaining immune homeostasis and immune tolerance. Previous studies showed that the generation of Tregs could be induced, and Tregs reduced the immune pathological damage to the host by inhibiting T-cell function in helminth infection.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • CD4-Positive T-Lymphocytes / immunology*
  • Helminthiasis / immunology*
  • Helminths / immunology*
  • Humans
  • Immune Tolerance
  • Interleukin-2 Receptor alpha Subunit / immunology

Substances

  • Interleukin-2 Receptor alpha Subunit