Magnetic resonance imaging of the liver after loco-regional and systemic therapy

Celia Pamela Corona-Villalobos; Yan Zhang; Wei-Dong Zhang; Ihab R Kamel

doi:10.1016/j.mric.2014.04.008

Magnetic resonance imaging of the liver after loco-regional and systemic therapy

Magn Reson Imaging Clin N Am. 2014 Aug;22(3):353-72. doi: 10.1016/j.mric.2014.04.008.

Authors

Celia Pamela Corona-Villalobos¹, Yan Zhang², Wei-Dong Zhang³, Ihab R Kamel⁴

Affiliations

¹ The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, 600 North Wolfe Street, MRI 110B, Baltimore, MD 21287, USA.
² The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, 601 North Caroline Street, Room 4240, Baltimore, MD 21287, USA; Department of Radiology, Shandong Medical Imaging Research Institute, 324 Jingwu Road, MRI, Jinan 250021, Republic of China.
³ The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, 601 North Caroline Street, Room 4240, Baltimore, MD 21287, USA.
⁴ The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, 600 North Wolfe Street, MRI 143, Baltimore, MD 21287, USA. Electronic address: [email protected].

PMID: 25086934
DOI: 10.1016/j.mric.2014.04.008

Abstract

Assessment of tumor response is crucial in determining the effectiveness of loco-regional and systemic therapy, and for determining the need for subsequent treatment. The ultimate goal is to improve patient's survival. Changes in tumor size and enhancement after therapy may not be detected early by the traditional response criteria. Tumor response is better assessed in the entire tumor volume rather than in a single axial plane. The purpose of this article is to familiarize the reader with early treatment response assessed by anatomic and volumetric functional magnetic resonance imaging metrics of the liver after loco-regional and systemic therapy.

Keywords: Biomarker; Contrast-enhanced MRI; Diffusion-weighted imaging; Loco-regional therapy; Response to therapy; Volumetric functional MRI.

Publication types

Review

MeSH terms

Biomarkers, Tumor
Contrast Media
Humans
Image Enhancement / methods
Liver / pathology*
Liver Neoplasms / pathology*
Liver Neoplasms / therapy*
Magnetic Resonance Imaging / methods*
Treatment Outcome

Substances

Biomarkers, Tumor
Contrast Media