Genetic diversity of bovine viral diarrhea viruses in commercial bovine serum batches of Chinese origin

Infect Genet Evol. 2014 Oct:27:230-3. doi: 10.1016/j.meegid.2014.07.021. Epub 2014 Aug 4.

Abstract

Bovine viral diarrhea virus (BVDV) is often detected in commercial bovine serum. BVDV genetic diversity was investigated in commercial bovine serum of Chinese origin. Twenty-two batches of bovine serum were obtained from 10 suppliers with different geographic origins in China, and 20 batches of bovine serum were positive by reverse-transcription polymerase chain reaction (RT-PCR) and sequencing. Phylogenetic reconstructions of partial 5'UTR sequences indicated that the samples examined in this work clustered within the BVDV type 1 and BVDV type 2 genotypes. Interestingly, 3 sample sequences clustered into CSFV. These results suggest a high genetic diversity in Chinese BVDV field isolates. This study will benefit epidemiological surveys of BVDV detected in China.

Keywords: Bovine serum; Bovine viral diarrhea virus (BVDV); Genetic diversity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 5' Untranslated Regions
  • Animals
  • Cattle
  • China
  • Diarrhea Viruses, Bovine Viral / classification
  • Diarrhea Viruses, Bovine Viral / genetics*
  • Genetic Variation*
  • Genotype
  • Hemorrhagic Syndrome, Bovine / virology*
  • Molecular Sequence Data
  • Phylogeny

Substances

  • 5' Untranslated Regions