The discovery of beta-galactosidase

Trends Biochem Sci. 1989 Oct;14(10):416-8. doi: 10.1016/0968-0004(89)90292-2.

Abstract

The enzyme beta-galactosidase was first mentioned in the literature by Beijerinck exactly a hundred years ago. The Department of Microbiology and Enzymology of the Delft University of Technology keeps the memory of Beijerinck, its first professor, alive by maintaining a 'Beijerinck-room' in the attic of the building. In addition to manuscripts and laboratory notebooks, this room contains some of his chemicals and biological preparations, and it was here that we recently found a 90-year old lactase preparation. Even after storage under suboptimal conditions, the preparation still exhibited measurable enzyme activities.

Publication types

  • Historical Article

MeSH terms

  • Galactosidases / history*
  • History, 19th Century
  • Netherlands
  • Saccharomyces / enzymology
  • beta-Galactosidase / history*

Substances

  • Galactosidases
  • beta-Galactosidase