When is the optimal time to screen for Chlamydia in adolescents and young adults with sickle cell disease?

Clin Pediatr (Phila). 2015 Feb;54(2):149-51. doi: 10.1177/0009922814545491. Epub 2014 Aug 6.

Abstract

Objectives: Louisiana has a high rate of chlamydia, an easily identifiable and treatable sexually transmitted disease. Patients with chronic diseases, such as sickle cell disease (SCD) often forgo routine primary care visits. We hypothesized that patients with SCD have an increased percentage of asymptomatic chlamydia compared with a matched population.

Methods: A retrospective cohort study was performed over a 12-month period on eligible patients with SCD (ages 15-30 years). Patients were screened for asymptomatic chlamydia by urine polymerase chain reaction during comprehensive care visits in the SCD clinic.

Results: Thirty-four patients underwent testing during the study period, and 4/34 patients (11.8%) tested positive for chlamydia. State data show a rate of 1791/100 000 (1.8%) among a demographically matched cohort.

Conclusions: Patients with SCD had a larger percentage of asymptomatic chlamydia than a demographically matched control population. Patients with SCD should be screened by specialists for chlamydia in addition to undergoing routine primary care evaluations.

Keywords: chlamydia; chronic disease; health care disparities; sickle cell disease.

MeSH terms

  • Adolescent
  • Adult
  • Anemia, Sickle Cell / epidemiology*
  • Chlamydia / isolation & purification*
  • Chlamydia Infections / diagnosis*
  • Chlamydia Infections / epidemiology*
  • Chlamydia Infections / urine
  • Cohort Studies
  • Comorbidity
  • Female
  • Humans
  • Louisiana / epidemiology
  • Male
  • Polymerase Chain Reaction
  • Retrospective Studies
  • Risk Factors
  • Young Adult