Biomarker and more: can translocator protein 18 kDa predict recovery from brain injury and myocarditis?

Biomark Med. 2014;8(5):605-7. doi: 10.2217/bmm.14.46.

Abstract

Translocator protein 18 kDa may be more than a simple detector of inflammation in the brain but may be intimately linked with severity and disease pathogenesis. Therefore, our understanding of translocator protein 18 kDa as a biomarker has circled back around to the brain.

Keywords: CD11b; biomarker; brain injury; complement; imaging; inflammation; myocarditis; sex difference; translocator protein 18 kDa.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biomarkers / metabolism
  • Brain Injuries / diagnosis
  • Brain Injuries / metabolism
  • Brain Injuries / physiopathology*
  • Female
  • Humans
  • Male
  • Mice
  • Myocarditis / diagnosis
  • Myocarditis / metabolism
  • Myocarditis / physiopathology*
  • Prognosis
  • Receptors, GABA / metabolism*
  • Recovery of Function*

Substances

  • Biomarkers
  • Receptors, GABA
  • TSPO protein, human